prostate – Enlarged (BPH)

Enlarged Prostate, BPH or Benign Prostatic Hyperplasia, is a condition involving the enlargement (hyperplasia) and Inflammation of the Prostate Gland. Enlarged Prostate can occurs in men over the age of 40 – approximately 45% to 50% of men are affected by Enlarged Prostate at some stage of their lives. The prevalence of Enlarged Prostate increases with age.  5% to 10% of men aged 30 experience Enlarged Prostate;  more than 90% of men over the age of 85 experience Enlarged Prostate. BPH are completely separated from Prostate Cancer.

 BPH can be start in men 
– Age 40 up to 9%
– Age 60 up to 60%
– Age 90 up to 80%

Substances may Cause Enlarged Prostate
– Diabetes Mellitus Type 2
 may increase the risk of Enlarged Prostate.
– Obesity may increase the risk of Enlarged Prostate.
– Protein Kinase C
 (Excessive activity) has been implicated in the development of Enlarged Prostate.
– 5-Alpha Reductase has been implicated in Enlarged Prostate (due to its role as a catalyst for the conversion of Testosterone to.   Dihydrotestosterone – excessive serum Dihydrotestosterone is strongly implicated as a cause of Enlarged Prostate).
– Elevated Prostate-Specific Antigen (PSA) levels may be a biomarker for Enlarged Prostate.
– Excessive Aromatase activity has been implicated in Enlarged Prostate (Aromatase is known to be present in the Prostate, where it catalyzes the conversion of Testosterone to Estradiol – Estradiol activity in the Prostate stimulates the growth of the Prostate).
– Dihydrotestosterone (DHT) may increase the risk of Enlarged Prostate.
– Excess Estradiol hormone levels may increase the risk of Enlarged Prostate.
– Excess Estrone hormone levels may increase the risk of Enlarged Prostate.
– Fibroblast Growth Factor is speculated to be involved in the development of Enlarged Prostate.
– Excessive Prolactin production may cause Enlarged Prostate.
– Exposure to Lead may cause Enlarged Prostate.
– Tobacco smoking may increase the risk of Enlarged Prostate.

Symptoms of Enlarged Prostate (BPH)
– Frequent Urination
– Incontinence
– Male Urinary Hesitancy
– Painful Urination
– Bladder can not empty
– Need to go soon after
– Bladder Stone

– Bleeding
– infection
– Complete inability to urine

Substances may Prevent/Alleviate Enlarged Prostate
– Amino acid (Alanine, Glycine
and Glutamic Acid) may minimize the symptoms of Enlarged Prostate when used in combination therapy.
– Melatonin
– Lycopene
– Omega-3 Fatty Acids
– Lauric Acid
– Beta-Sitosterol
– Zinc
– Selenium
– 

Dr. Said Sokhandan
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