prostate – Enlarged (BPH)

Enlarged Prostate, BPH or Benign Prostatic Hyperplasia, is a condition involving the enlargement (hyperplasia) and Inflammation of the Prostate Gland. Enlarged Prostate can occurs in men over the age of 40 – approximately 45% to 50% of men are affected by Enlarged Prostate at some stage of their lives. The prevalence of Enlarged Prostate increases with age.  5% to 10% of men aged 30 experience Enlarged Prostate;  more than 90% of men over the age of 85 experience Enlarged Prostate. BPH are completely separated from Prostate Cancer.

 BPH can be start in men 
Age 40 up to 9%
Age 60 up to 60%
Age 90 up to 80%

Substances may Cause Enlarged Prostate
– Diabetes Mellitus Type 2
 may increase the risk of Enlarged Prostate.
– Obesity may increase the risk of Enlarged Prostate.
– Protein Kinase C
 (Excessive activity) has been implicated in the development of Enlarged Prostate.
– 5-Alpha Reductase has been implicated in Enlarged Prostate (due to its role as a catalyst for the conversion of Testosterone to.   Dihydrotestosterone – excessive serum Dihydrotestosterone is strongly implicated as a cause of Enlarged Prostate).
– Elevated Prostate-Specific Antigen (PSA) levels may be a biomarker for Enlarged Prostate.
– Excessive Aromatase activity has been implicated in Enlarged Prostate (Aromatase is known to be present in the Prostate, where it catalyzes the conversion of Testosterone to Estradiol – Estradiol activity in the Prostate stimulates the growth of the Prostate).
– Dihydrotestosterone (DHT) may increase the risk of Enlarged Prostate.
Excess Estradiol hormone levels may increase the risk of Enlarged Prostate.
Excess Estrone hormone levels may increase the risk of Enlarged Prostate.
– Fibroblast Growth Factor is speculated to be involved in the development of Enlarged Prostate.
Excessive Prolactin production may cause Enlarged Prostate.
Exposure to Lead may cause Enlarged Prostate.
– Tobacco smoking may increase the risk of Enlarged Prostate.

Symptoms of Enlarged Prostate (BPH)
– Frequent Urination
– Incontinence
– Male Urinary Hesitancy
– Painful Urination
– Bladder can not empty
– Need to go soon after
– Bladder Stone

– Bleeding
– infection
– Complete inability to urine

Substances may Prevent/Alleviate Enlarged Prostate
– Amino acid (Alanine, Glycine
and Glutamic Acid) may minimize the symptoms of Enlarged Prostate when used in combination therapy.
– Melatonin
– Lycopene
– Omega-3 Fatty Acids
– Lauric Acid
– Beta-Sitosterol
– Zinc
– Selenium
– 

Dr. Said Sokhandan
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