Stroke – DR. Said Sokhandan, N.D.

Insulin Resistance

Dr. Said Sokhandan — Wed, 10 Mar 2021 09:15:07 +0000

Insulin Resistance is a condition that involves a decrease in the sensitivity of the body’s Cells to the actions of Insulin (i.e. a decrease in Insulin Sensitivity). Insulin Resistance is characterized by decreased sensitivity of Insulin Receptors for Insulin. This lack of sensitivity to the effects of Insulin results in ever-increasing production of Insulin, to the extent that dangerously high levels of Insulin can occur. 25% of the population of the United States has Insulin Resistance (presumably this statistic would apply also to most other Western nations). Insulin facilitates the transport of Vitamin C into Cells and the Insulin Resistance that afflicts Diabetes Mellitus patients may therefore impair the transport of Vitamin C into Cells.
– 6.7% of persons aged 20 – 29 have Insulin Resistance.
– 43.5% of persons aged 60 – 70 have Insulin Resistance

Substances may Cause Insulin Resistance
– Excessive consumption of Fructose may cause Insulin Resistance
– Excessive consumption ofSucrose may cause Insulin Resistance
– Excessive consumption ofCarbohydrates may cause Insulin Resistance
– Excessive consumptionCaffeine may cause Insulin Resistance
– Excessive consumption of Soft Drinks may cause Insulin Resistance
– Excessive consumption of Alcohol may cause Insulin Resistance
– Excessive endogenous production or release o fInsulinmay cause Insulin Resistance (via a Negative feedback)
– Excessive production of Cortisol may cause Insulin Resistance in the Muscles
– ExogenousEstrogensmay increase the risk of Insulin Resistance in postmenopasual women using Estrogens as part of Hormone Replacement Therapy (HRT)
– Excessive consumption of Saturated Fatty Acids and Trans-fatty Acid may cause Insulin Resistance
– C-Reactive Protein is a biomarker of Insulin Resistance
– Elevated Uric Acid levels may cause Insulin Resistance
– Obesity may increase the risk of Insulin Resistance
– Excessive Stress may cause Insulin Resistance
– A high Glycemic Index diet may increase the risk of Insulin Resistance

Insulin Resistance may be Associated with these Ailments
– Insulin Resistance may increase the risk of Heart Attack
– Insulin Resistance may increase the risk of Ischemic Heart Disease (due to the elevated Insulin levels that are associated with Ischemic Heart Disease)
– Insulin Resistance may cause Hypertension
– Insulin Resistance may cause Stroke
– Insulin Resistance may contribute to the development of Alzheimer’s Disease
– Insulin Resistance is a symptom of and is the primary feature of Diabetes Mellitus Type 2
– insulin Resistance may increase the risk of Atherosclerosis
– Insulin Resistance may increase the risk of Breast Cancer
– Insulin Resistance may increase the risk ofProstate Cancer
– Insulin Resistance may causePolycystic Ovary Syndrome (PCOS) , there is some evidence that Insulin Resistance is the principal underlying cause of (PCOS)
– Insulin Resistance may cause the Nonalcoholic Steatohepatitis (NASH) form of Fatty Liver
– Insulin Resistance may result in elevated serum Cholesterol, Triglycerides levels and lower the HDL Cholesterol
– Insulin Resistance may be the underlying cause of Fatigue

Substances may Decrease Insulin Resistance
– some Amino acid may reduce Insulin Resistance (Arginine, Leucine, Taurine and NAC)
– DHEA
– Testosterone
– Melatonin

Lipids
– Conjugated Linoleic Acid (CLA)
– Gamma Linolenic Acid (GLA)
– Alpha-Linolenic Acid (LNA)
– Omega-3Fatty Acid
– Docosahexaenioc Acid (DHA)
– Eicosapentaenoic Acid (EPA)

Minerals
– Calcium
– Magnesium
– Potassium
– Selenium
– Chromium
– Zinc
– Coenzym Q10 may reduce Insulin Resistance

Vitamins
– Vitamin C
– Folic Acid
– Vitamin A
– Biotin
– Vitamin D
– Vitamin E
– Vitamin K
– Lipoic Acid

Herbs
– Ginger
– Cinnamon
– Bitter Melon
– Green Tea
– Chia seeds
– Grape Seeds
– Fengreek Seeds

Dietary oils
– Fish oil
– Cod liver Oil

Exercise
– Regular Exercise may reduce Insulin Resistance
– Aerobic
– Isotonic

Obesity

Dr. Said Sokhandan — Sun, 30 Aug 2020 08:35:04 +0000

The term Obesity is applied to persons who are more than 20% above their recommended body weight as measured by Body Mass Index. Another means of determining Obesity is the Waist-to-Hip Ratio. approximately 35% of Men and 40%.women in US. A healthy body fat percentage for women is 21% to 35% and for men a healthy body fat percentage is 12% to 25%. One pound of human body fat contains 3,500 calories. In the USA, approximately 21% – 24% of children are obese or overweight. The ideal body water percentage for men ranges from 50% to 65% for women ranges from 45% to 60%. Approximately 7% of the world’s total population is obese.

Causes of Obesity
– A high–Glycemic Index diet may increase the risk of Obesity
– Excessive consumption of fried Frying foods and Fast food due to high calories.
– Binge Eating.
– Excessive consumption of Simple Sugar (Glucose, Sucrose and Fructose).
– Excessive consumption of dietary Carbohydrates.
– .Excessive consumption of Dietary Fats.
– Excess consumption of calories increase the risk of Obesity.
– Trans-Fatty Acids may increase the size and quantity of Adipose Tissue (body Fat).
– Environmental toxin exposure like (Bisphenol A) may contribute to Obesity.
– Excessive consumption of Monosodium Glutamate (MSG) may cause Obesity.
– High levels of Cortisol contribute to the development of Obesity.
– Elevated Insulin levels and Insulin Resistance may increase the risk of Obesity.
– Excessive production/release of Prolactin may contribute to Obesity.
– High levels of Reverse T3 may cause Obesity.
– Excessive Zinc has been associated with Obesity.

Obesity may cause;
– May increases the risk for Hypertension (high Blood Pressure).
– May increase the risk of Cardiovascular Diseases.
– May increase the risk for Ischemic Heart Disease.
– May increase the risk of (ischemic) Stroke.
– May increase the risk of Pulmonary Hypertension.
– May increase the risk of Atherosclerosis.
– May increase the risk of Varicose Veins.
– May increase the risk of Kidney disease and Kidney Stones.
– May impair Immune system that May increase the risk of Viral diseases and Bacterial infections.
– May increase the risk of some forms of Cancer (breast Cancer, cervical Cancer, Uterus, Endometrial, Ovarian, Prostate,
Pancreatic, Skin…….).
– May increase the risk of elevated serum Cholesterol levels and lower HDL Cholesterol.
– may increase the risk for developing Diabetes Mellitus Type 2.
– May increase the risk of Backache and Knee Pain.
– May increase the risk of Osteoarthritis.
– May cause Carbohydrate Cravings.
– May increase the risk of Gout.
– May increase the risk of Depression (due to increased Cortisol causing Serotonin depletion).
– May increases the risk of Sleep Apnea.
– May increase the risk of Asthma.
– may increase the risk of Polycystic Ovary Syndrome (PCOS) (approximately 40% of PCOS patients are overweight).
– may increase Uric Acid levels.

Progesterone

Dr. Said Sokhandan — Sat, 22 Aug 2020 08:35:59 +0000

Progesterone is a Sexual Steroid Hormone secreted by the Ovaries, Placenta and in small amounts by the Adrenal Cortex and in males the Testes. Progesterone is a female hormone, which is a great factor for the regulation of ovulation and menstruation and excessive or prolonged bleeding during Menstruation) is often caused by sub-optimal Progesterone levels, in many female Low serum Progesterone levels may cause Pre-Menstrual Syndrome (PMS). The female body’s endogenous production of Progesterone falls to zero (or very close to zero) during and for some time prior to Menopause (Female).
Progesterone may help to prevent many types of Cardiovascular Diseases (due to its ability to minimize risk factors for Cardiovascular Diseases such as elevated LDL Cholesterol, lowered HDL Cholesterol and elevated Triglycerides levels).
Progesterone may help to prevent High Blood Pressure (by facilitating the excretion of excessive Sodium from the body).
Progesterone may facilitate recovery from (ischemic) Stroke.
Progesterone as Hormone Replacement Therapy (HRP) is poorly absorbed when administered orally. Exogenous Progesterone as Hormone Replacement Therapy (HRP) is absorbed extremely efficiently through the Skin (in the form of a topically applied cream). The site of topical application of Progesterone should be rotated between the Breasts, Abdomen and Thighs in order to avoid over-saturation of any given region.

Biological Function of Progesterone
1- May help to prevent Heart Attack.
2- May help to prevent High Blood Pressure.
3- May help to facilitate recovery from Stroke (ischemic).
4- May protect against the Hair Loss.
5- May help to prevent Cancer – Uterus, Breast and Endometrium.
6- May inhibit the growth of Cancer – Prostate cells (by inhibiting the conversion of Testosterone to Dihydrotestosterone (DHT) by inhibit the activity of 5 Alpha-Reductase.
7- May lower elevated serum Triglycerides,, Cholesterol, LDL (Low Density Lipoprotein) and may increase HDL(High Density Lipoprotein).

8- May prevent and possibly revers Osteoporosis (by stimulating Osteoblast activity), Osteoblast-mediated Bone formation.
9- May facilitate the excretion of excessive Sodium from the body (due to Progesterone competing with Aldosterone for occupancy of the Kidneys)
10- may facilitate the formation and maintenance of Myelin Sheets.
11- Decline in Progesterone production may be involved in Postpartum – Depression.
12- may alleviate and may help to prevent some forms of Depression.
13- may help to restore normal Sleep cycles.
14- may alleviate Ovarian Cysts.
15- may alleviate Uterine fibroids (by counteracting the estrogens dominance that is the underlying cause of many cases of Uterine Fibroids).

Substances may Enhance the Function of Progesterone
1- Prolactin stimulates the production of Progesterone within the Ovaries
2- (LH) Luteinzing Hormone stimulates the Corpus Luteum during the Luteal Phase of the Menstrual Cycle to produce Progesterone
3- Vitamin C may increase Progesterone production in Luteal Phase Defect patients
4- Vitamin E
5- Vitamin B6
6- Vitamin B5
7- The Retinoic acid form of Vitamin A may enhance the production of Pregnenolone in the Central Nervous System.

Omega-3

Dr. Said Sokhandan — Wed, 12 Aug 2020 08:43:10 +0000

Omega-3 Fatty Acids also called omega-3 oil they play an important role in human physiology and diet.

Three type of Omega-3
1– Alpha-LInolenic acid (ALA) Fund in plant oils edible seeds (walnuts, Flaxseed, Hemp….).
2- Ecosapentaenoic Acid in marine oils ( fish, Krill, Eggs and certain Algae).
3- Docosahexaaenoic Acid in marine oils ( fish, Krill, Eggs and certain Algae) .

Health Benefits of Omega-3 Fatty acid
1- May Prevent Cardiovascular Diseases (CVD) by inhibiting the production of Apoprotein (a) (Apo (a)).
2- May Prevent High blood pressure
3- May Prevent Atherosclerosis
4- May Prevent Heart Attack
5- May Prevent Strok
6- reduce the Inflammation associated with Colitis
7- May Prevent Crohn’s Disease
8- Prevent Gallstones
9- may help to prevent Age- Related Macular Degeneration (ARMD)
10- may help to prevent and treat Autoimmune Disease
11- may help to prevent Fatty Liver
12- may lower elevated serum Triglycerides levels.
13- May lower elevated Homocysteine

Fish high in Omega-3 Fatty Acid
1- King Salmon
2- Mackerel
3- Herring
4- Sardines
5- Trout
6- Tuna

Fish Oils may Counteract Potentially Toxic effects of:
1- May inhibit the excessive production of Cytokines (Interleukin 1, Interleukin 6, and Tumor Necrosis Factor).
2- May reduce Creatine Phosphokinase (CPK) levels in persons who undertake intensive exercise.
3- May inhibit the ability of (mental) stress to increase Cortiso levels.
4- May help to reduce the toxic side effects of Anti Cancer Medicinal Drug.
5- May lower C-Reactive Protein levels.
6- May lower the body’s production of Archidonic acid.
7- may lower elevated Fibrinogen levels.
8- May help to prevent Alcoholl-induced Fatty Liver.
9- may lower elevated serum Triglycerides and increase HDL levels in tobacco smokers.

Toxic Effects of Fish Oils
1- May cause Diarrhea in some people.
2- May cause temporary Gastrointestinal discomfort in some people.
3- May increaseLDL Cholesterol levels (12grams /day) that may cause the depletion of Vitamin E.