osteoporosis – DR. Said Sokhandan, N.D.

Estrogen- Female Sexual Steroid Hormones

Dr. Said Sokhandan — Mon, 17 Aug 2020 06:11:36 +0000

Estrogen

Estrogen is the primary Female Sexual Steroid Hormones is responsible for the reproduction for the development and regulation of the female reproductive system and produced in the Ovaries and (to a lesser extent in males) the Testes.

Estrogen may inhibit the rate of Bone loss that occurs during Osteoporosis by inhibiting the production of Interleukin 6 which in turn inhibits the production of Osteoclasts).
Estrogen may help to prevent Alzheimer’s Disease via numerous mechanisms. Endurance Exercise may reduce womens’ levels of Estrogens.

3 Type of Estrogen

1- Estradiol
– Estradiol is the major (most biologically potent) Estrogen produced and secreted by the female Ovaries (and produced in smaller
quantities in males). There are two forms of Estradiol (of which Estradiol 17-Beta is the most biologically potent).
– Estradiol (especially natural Estradiol used in post-menopausal Estrogen Replacement Therapy (ERT)) may help to prevent
Alzheimer”s Disease. Estradiol may help to maintain normal Brain function.
– May help to prevent Anxiety.
– may increase (female) Sexual Desire (by stimulating the endogenous production of Nitric Oxide Synthase (NOS) which catalyzes
the production of Nitric Oxide (NO).
– May inhibit toxic effects of Amyloid-Beta Protein to destroy Neurons
– High level of Estradiol (in males or females) may increase the risk of Breast Cancer (Estradiol strongly stimulates the growth of Breast tissue.
– High level of endogenous Estradiol levels (in males) may increase their risk of Heart Attack and Stroke.
– High level of endogenous production of Estradiol may cause Endometrial Cancer, Ovarian, and Uterus Cancer.
– High level of Estradiol levels (in males) may increase the risk of Enlarged Prostate.
– Vitamin may reduce elevated Estradiol level (Choline, Inositol, E, and B6)

2- Estriol

– Estriol is a estrous,weak estrogen also known as (16 Alpha Hydroxyestradiol) and involved in pregnancy.
– May alleviate the Urinary Incontinence that commonly occurs in association with Female Menopause.
– May help to prevent Osteoporosis
– Estriol cream applied intravaginally, may alleviate Vaginal Atrophy.

3- Estrone

– Estrone come from the overies, as well as the adipose tissue and adrenal glands.
– Excessive production of Estrone (and impaired conversion of Estrone to Estriol within the Liver) has been closely linked to
(Breast cancer, Ovarian Cancer, Uterus cancer, and Endometrial cancer).
– Excessive production of Estrone in men may increase the risk of Prostate Cancer.

Biological Function of Estrogens
– May improve Blood Circulation to the Brain
– May inhibit the rate of Bone loss that occurs during Osteoporosis ( by inhibiting Interleukin 6)
– May help to prevent Alzheimer in Post- menopausal women
– May increase High density lipoprotein (HDL) and Low density lipoprotein (LDL)
– May improve Memory
– May help to prepare the female body for Pregnancy
– May increase the moisture content of the Skin
– May increase the quantity of Type IIICollagen in the Skin
– May improve the elasticity and firmness of the Skin
– May enhance the retention of Calcium in the Bones

Estrogens may Interfere with these Substances
– May increase the body’s requirement for Vitamin E
– May deplete the body’s FolicAcid levels
– May interfere with Vitamin B6
– May interfere with Biotin
– May deplete Choline
– May deplete the body’s Inositol levels

OSTEOPOROSIS

Dr. Said Sokhandan — Sun, 09 Aug 2020 06:38:44 +0000

Osteoporosis is a condition where Bones become porous, brittle and less dense as a result of a loss of Bone mass. Bone loss accelerates to 3% – 5% per year for approximately five years, after which Bone loss continues at the rate of approximately 1.5% per year. Most often People with osteoporosis breaks their bones in the area like hip, forearm, wrist, and spine. While most broken bones are caused by falls, osteoporosis can weaken bones to the point that a break can occur more easily. As you get older, you are more likely to have osteoporosis and recovering from a broken bone becomes harder. Broken bones can have lasting effects including pain that does not go away. Osteoporosis can cause the bones in the spine to break and begin to collapse, so that some people with it get shorter and are not able to stand up straight. Broken hips are very serious can cause many other health issue. 33% of females and 15% of males experience a Hip Fracture by the age of 90 (Hip Fractures almost always occur as a result of Osteoporosis). post-Menopausal women have the highest incidence of Osteoporosis(due to female bioavailability of Calcium decreasing after the Menopause and also due to Calcium being “leached” from the Bones of females during Pregnancy and Lactation). 25% – 30% of white and oriental women; and 20% of black women; develop Osteoporosis.

Who is more prone to osteoporosis
1- Menopause females 33% and males 15% and osteoporosis 4 times as likely in women than men.
2- Hereditary can be element to the risk of developing osteoporosis
3- malnutrition and malabsorption person have high risk of developing osteoporosis
4- underweight person have a high risk of developing osteoporosis

What substance can increase the risk of Osteoporosis
1- Homocysteine; Homocysteine interferes with optimal Collagen Cross-linking, resulting in impaired structure of the Bone matrix).
2- Caffeine; Excessive consumption of caffeine may increase the risk of Osteoporosis proses.
3- Cortisol; Excessive production of Cortisol may cause Osteoporosis
4- Exogenous (LHRH); Luteinizing Hormone Releasing Hormone should not be used longer than six months that may increase the risk of Osteoporosis.
5- Excessive activity of immune system
6- Saturated fatty acid;
7- Exposure to excessive minral;
* Aluminium
* Fluoride
* phosphorus (carbenated drink)
* sodium.
8- Pharmaceutical Drugs;
* antiacid
* Proton pump inhibitors
* Glucocorticosteroids
* Prednisone
* Diuretics
* Laxatives
9- Recreational Drugs
* Alcohol
* Tabacco
10- Inflammation
11- Free radicals
12- Endurance exercise (triathletes)
13- Crohn’s Disease
14- insufficient production of Hydrochloric acid (Hypochlohydria)
15- Ulcerative Colitis
16-Hypothyroidism

Substances may Alleviate/Prevent Osteoporosis

Hormones

1-Estrogen
2- Estriol
3- Estrone
4- Progestrone; Progesterone deficiency may be a major cause of Osteoporosisand clinical studies have shown that supplemental Progesterone may increase bone mass density (BMD) by 7% after 1 year of supplementation, by 12% after two years, and by 15% after three years. Women administered supplemental Progesterone up to the age of 80 following Menopause often exhibit strong Bones without evidence of Bone loss while continuing to use natural Progesterone.
5- HGH
6- Pregnenolone
7- Testosterone
8- Omega-3 fatty acids
9- Calcium
10- Magnesium
11- Manganese
12- Silicon
13- Potassium
14- Folic acid as metafolate
15- B12
16- Vit C
17- Vit D3
18- Vit K2, K7
19- Black Cohosh
20- Exercise; Regularly 2-5 times a week

Calcium deficiency and symptoms

Dr. Said Sokhandan — Mon, 03 Aug 2020 21:14:33 +0000

Calcium plays major to build and maintain strong bones. Calcium is necessary for function of heart, muscles and nerves.Some studies suggest that calcium, along with vitamin D, may benefit bone health and perhaps protecting against cancer, diabetes, weight and high blood pressure. Calcium plays a major role in our health and the bones and the teeth, but this bone-building mineral is also significant in other areas of our health, including weight management and decreasing PMS symptoms. Post-Menopausal women absorb Calcium less efficiently – this contributes to their greater risk of Osteoporosis.

Health Benefits of Calcium
– May enhance the function of the AdrenalGland
– May lower Blood Pressure
– May help to prevent Kidney Stones
– Abnormalities in Calcium may be an important factor in the pathogenesis of Hypertension
– May help to prevent (both forms of) Stroke
– May normalize heart rhythm in Arrhythmias patients
– Calcium can help and prevent constipation and alleviate heartburn
– May help to alleviate Gastric ulcer
– Calcium can help to prevent some forms of cancer ( Brian, Meningioma, colon and Ovarian )
– May lower total serum Cholesterol level by up to 6% and help to increase HDL, also decrease LDL level by 11%.
– 98% of the body”s Calcium is concentrated in the Bones where Calcium is involved in the formation and growth of the Bones. Optimal Calcium intake may help to prevent
Fractures, and There is a strong relationship between Calcium deficiency and Osteoporosis
– May help Bone Pain
– May help Joint Pain and some Backache
– May help Muscle Weakness and Muscle Cramps
– May help to prevent Cataracts
– May prevent cancer ( Colon, Ovarian and Brain )
– May be useful for the prevention/treatment of Alzheimer’s disease (it may activate the Choline Acetylase enzyme that generates Acetylcholine, the Neurotransmitter that is
most dysfunctional in Alzheimer”s Disease patients).

Dietary Sources of Calcium (mg of Calcium per 100 grams)

Grains
wheat Bran 119
Buckwheat 114
wheat Germ 72
Ray 38

Dair
Swiss cheese 950
whey powder 646
Cow’s milk 115
Milk goat’s 129
Eggs yolk 131

Seafoods
Scallops 115
Salmon 105

Legumes
Chick peas 150
Mung Beans 118

Nuts
Almonds 245
Hazelnuts 188
Brazil nuts 186
Pistachio 131

Fruits
figs 240
Olive 106
Apricot 67
Dates 59

Vegetables
Kale 249
Watercress 192
Broccoli 123
Onions 136
Sweet Potato 32

Herbs
Parsly 203
Dandelion leaves 187