Substances may Cause Insulin Resistance
– Excessive consumption of Fructose may cause Insulin Resistance
– Excessive consumption ofSucrose may cause Insulin Resistance
– Excessive consumption ofCarbohydrates may cause Insulin Resistance
– Excessive  consumptionCaffeine may cause Insulin Resistance
– Excessive consumption of Soft Drinks may cause Insulin Resistance
– Excessive consumption of Alcohol may cause Insulin Resistance
– Excessive endogenous production or release o fInsulinmay cause Insulin Resistance (via a Negative feedback)
– Excessive production of Cortisol may cause Insulin Resistance in the Muscles
– ExogenousEstrogensmay increase the risk of Insulin Resistance in postmenopasual women using Estrogens as part of Hormone Replacement Therapy (HRT)
– Excessive consumption of Saturated Fatty Acids and Trans-fatty Acid may cause Insulin Resistance
– C-Reactive Protein is a biomarker of Insulin Resistance
– Elevated Uric Acid levels may cause Insulin Resistance
– Obesity may increase the risk of Insulin Resistance
– Excessive Stress may cause Insulin Resistance
– A high Glycemic Index diet may increase the risk of Insulin Resistance

C-Reactive Protein (CRP) is an inflammatory marker often checked in blood test to determine level of inflammation in the body. C-Reactive Protein that can be used to predict heart attack risk.  It is produced by the Liver and released in response to acute injury, Bacterial & Viral Infection or other causes of Inflammation that causes increase of CRP. The body releases CRP into the bloodstream when Blood Vessels leading to the Heart are damaged, a common result of Atherosclerosis.  C-Reactive Protein level indicates the degree of Inflammation occurring in the lining of the Arteries. C-Reactive Protein is a biomarker of abnormal Blood Clotting (its presence is indicative of destabilized atherosclerotic plaque that can cause abnormal Blood Clotting). C-Reactive Protein is a biomarker of future Heart Attack risk (its presence is indicative of destabilized atherosclerotic plaque that can cause Heart Attacks).  People with high levels of C-Reactive Protein are three times more likely to die from a future Heart Attack than people with low levels of C-Reactive Protein. The Brains of Alzheimer’s Disease patients contain higher than normal levels of C-Reactive Protein and also patients with Dementia have  higher than normal levels of C-Reactive Protein in there brain.

Toxic Effects of C-Reactive Protein
–  Biomarker of Inflammation
– Biomarker of future Hypertension risk
– biomarker of future Heart Attack
– biomarker of Dilated Cardiomyopathy
– Biomarker of future Stroke
– Biomarker of abnormal Blood Clotting
– biomarker of Atherosclerosis
– May be a biomarker of (acute) Pancreatitis
– May be a biomarker of future risk of Cataracts
– May be a biomarker forAge-Related Macular Degeneration (ARMD)
–  May be a biomarker for Cancer (Colon and Prostate)
– May be a biomarker of Insulin Resistance
– May be a biomarker of Diabetes Mellitus Type 2
– Biomarker of Crohn’s Disease
– May be a biomarker of Rheumatic Fever
– May be a biomarker of Rheumatoid Arthritis
– May be a biomarker of Fractures

Substances may Lower C-Reactive Protein Levels
– Dietary Fiber
– DHEA
-Arginine
– Selenium
– Magnesium
– Folic Acid
– Vitamin B6
– Vitamin D
– Vitamin C
-Vitamin E
– Curcumin
– Resveratrol
– Eicosapentaenoic Acid (EPA)
– Omega-3 Fatty Acid
– Fish Oil
– Krill Oil
– Flax Seed grained or oil
– Nuts
– Who; Grains
– Probiotic (Lactobacillus)
– Red Yeast Rice
– Quercetin
– Wine
– Chocolate
– Patented Medicines (Aspirin and Ibuprofen)

Substances may Increase C-Reactive Protein Levels
– Immune System Chemicals (Interleukin-1, Interleukin-6 and Tumor Necrosis Factor)
– Conjugated Estrogens
– Trans-Fatty Acids
– More than one cup a day Coffee
– Tabacco

Toxic Effects of Excessive Caffeine Consumption
–  May irritate the Kidneys
– May cause Kidney Stones (due to Caffeine increasing urinary Calcium excretion)
–  May increase the risk of Hypertension (blood Pressure)
– May increase levels of Lactic Acid in the Muscles of people who undertake Endurance Exercise
– May irritate the Bladder
– May cause Insulin Resistance
– May increase the risk of Osteoporosis
– May increase the risk ofFibrocystic Breast Disease
– Regular consumption of Caffeine may increase the incidence of Headaches
– May trigger Migraines in some people
– Consume Caffeine at night time may interrupted sleep produces fewer periods of Slow Wave Sleep (Deep Sleep)
– may cause (temporary) Tremor
– May increase the risk of Miscarriage
– May increase the risk of Female and male Infertility
– May increase the risk of Pre-Menstrual Syndrome(PMS)

Health Benefits of Caffeine
– Stimulating the production and secretion of Hydrochloric acid
– Negative impact in Cancer (Breast) could provide health benefits
– May increase the body’s Basal Metabolism
–  May increase Energy levels
– May temporarily)improve Athletic Performance
– May increase Muscle Strength by stimulating the release of Calcium in Muscle Fibers
– May improve Stamina
–  May delay the onset of Fatigue
– May stimulate the flow of Bile from the Liver
– May stimulate the Cerebral Cortex of the Brain
– May increase Alertness
– May relieve the symptoms of Hay Fever

Side Effects of Caffeine Withdrawal
– Anger
– Muscle Tension
– Vomiting
– Nausea
– Headaches
– Drowsiness
– Irritability
– Anxiety
– Sleep Disturbance