Estrogen is the primary Female Sexual Steroid Hormones is responsible for the reproduction for the development and regulation of the female reproductive system and produced in the Ovaries and (to a lesser extent in males) the Testes.

Estrogen may inhibit the rate of Bone loss that occurs during Osteoporosis by inhibiting the production of Interleukin 6 which in turn inhibits the production of Osteoclasts).
Estrogen may help to prevent Alzheimer’s Disease via numerous mechanisms. Endurance Exercise may reduce womens’ levels of Estrogens.

3 Type of Estrogen

1- Estradiol
– Estradiol is the major (most biologically potent) Estrogen produced and secreted by the female Ovaries (and produced in smaller
quantities in males). There are two forms of Estradiol (of which Estradiol 17-Beta is the most biologically potent).
– Estradiol (especially natural Estradiol used in post-menopausal Estrogen Replacement Therapy (ERT)) may help to prevent
Alzheimer”s Disease. Estradiol may help to maintain normal Brain function.
– May help to prevent Anxiety.
– may increase (female) Sexual Desire (by stimulating the endogenous production of Nitric Oxide Synthase (NOS) which catalyzes
the production of Nitric Oxide (NO).
– May inhibit toxic effects of Amyloid-Beta Protein to destroy Neurons
– High level of Estradiol (in males or females) may increase the risk of Breast Cancer (Estradiol strongly stimulates the growth of Breast tissue.
– High level of endogenous Estradiol levels (in males) may increase their risk of Heart Attack and Stroke.
– High level of endogenous production of Estradiol may cause Endometrial Cancer, Ovarian, and Uterus Cancer.
– High level of Estradiol levels (in males) may increase the risk of Enlarged Prostate.
– Vitamin may reduce elevated Estradiol level (Choline, Inositol, E, and B6)

2- Estriol

– Estriol is a estrous,weak estrogen also known as (16 Alpha Hydroxyestradiol) and involved in pregnancy.
– May alleviate the Urinary Incontinence that commonly occurs in association with Female Menopause.
– May help to prevent Osteoporosis
– Estriol cream applied intravaginally, may alleviate Vaginal Atrophy.

3- Estrone

– Estrone come from the overies, as well as the adipose tissue and adrenal glands.
– Excessive production of Estrone (and impaired conversion of Estrone to Estriol within the Liver) has been closely linked to
(Breast cancer,   Ovarian Cancer, Uterus cancer, and Endometrial cancer).
– Excessive production of Estrone in men may increase the risk of Prostate Cancer.

Biological Function of Estrogens
–  May improve Blood Circulation to the Brain
– May inhibit the rate of Bone loss that occurs during Osteoporosis ( by inhibiting Interleukin 6)
– May help to prevent Alzheimer in Post- menopausal women
– May increase High density lipoprotein (HDL) and Low density lipoprotein (LDL)
– May improve Memory
– May help to prepare the female body for Pregnancy
– May increase the moisture content of the Skin
– May increase the quantity of Type IIICollagen in the Skin
– May improve the elasticity and firmness of the Skin
– May enhance the retention of Calcium in the Bones

Estrogens may Interfere with these Substances
– May increase the body’s requirement for Vitamin E
– May deplete the body’s FolicAcid levels
– May interfere with Vitamin B6
– May interfere with Biotin
– May deplete Choline
– May deplete the body’s Inositol levels